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  In a review of 34 studies with a total of 112,027 participants from both high-income countries (HIC) and low-income or middle-income countries (LMIC), the authors, led by F. Gerald R. Fowkes, PhD, of the University of Edinburgh in Edinburgh, U.K., found that while PAD is on the rise around the world, the 10-year increase has been greatest in LMIC, at 28.7 percent, compared with 13.1 percent in HIC. About 70 percent of people with PAD are living in LMIC.

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